Path
Gut Repair
A leaking intestinal barrier produces endotoxin that drives systemic inflammation downstream. Fix the barrier first; everything else compounds.
For: IBS, food sensitivities, post-antibiotic dysbiosis, or chronic skin inflammation.
◆ 10 quizzes◆ 10 slide decks
Learning objectives · Bloom-aligned · 12
- understandExplain the tight junction–zonulin–LPS cascade that defines leaky gut pathophysiology
- analyzeAnalyze why barrier repair must precede microbiome modulation in the leaky-gut sequence
- applyApply the Phase 1 BPC-157 and KPV stack to rebuild gut wall integrity across Weeks 1-4
- evaluateEvaluate Thymosin Alpha-1 and LL-37 mechanisms for restoring mucosal Treg balance and clearing dysbiotic biofilm
- analyzeAnalyze the HPA-gut loop and explain how sympathetic dominance stalls barrier repair via vagal tone suppression
- evaluateInterpret zonulin, calprotectin, LPS, and GI-MAP results as leading vs lagging markers of gut barrier status
- applyExecute the Week 1-4 oral BPC-157 and KPV dosing schedule with realistic compliance scaffolding
- applyApply the Week 5-10 layered protocol stacking Thymosin Alpha-1 and LL-37 onto the Phase 1 maintenance floor
- evaluateEvaluate Week 8 lab response patterns and select the clear, partial, or no-response branch protocol
- createCreate a personalized maintenance plan combining low-dose BPC-157 cycling, quarterly TA-1 pulses, and lifestyle anchors
- analyzeAnalyze the connective-tissue repair mechanism of BPC-157 as it applies to gut wall versus systemic tissue
- createCreate an integrated protocol sequencing barrier repair, immune retraining, vagal restoration, and lab-guided adjustment into a 10-week arc
Chapters · 10
- 01What's actually happening in leaky gut
- 02The upstream lever barrier first not biome first
- 03Chapter 3 — Phase 1 reset (Week 1-4): BPC-157 and KPV barrier rebuild
- 04Chapter 4 — Phase 2 rebuild (Week 5-10): Thymosin Alpha-1 and LL-37 immune retraining
- 05Supporting axis — vagal tone, cortisol, and the HPA-gut loop
- 06Labs that matter zonulin calprotectin lps and the gi map
- 07Weeks 1-4 execution — the daily and weekly rhythm
- 08Weeks 5-10 execution — layering Thymosin Alpha-1 and LL-37
- 09Adjusting based on labs clear partial and no response
- 10Chapter 10 — Maintenance and sustained remission: the forever floor
Research use only · Not medical advice