Path
Muscle Gain
Your 20s hypertrophy ran on borrowed time. The same protocol — 4-day split, 30g protein post-lift, sleep, repeat — built visible muscle then because three biological systems were…
For: See chapter one for the full framing.
◆ 10 quizzes◆ 10 slide decks
Learning objectives · Bloom-aligned · 11
- analyzeAnalyze how age-related decline in pulsatile GH secretion and satellite cell activity blunts mTOR-driven hypertrophy in adult muscle
- analyzeDifferentiate restoring endogenous pituitary GH pulse from exogenous hormone stacking as the upstream lever for adult recomposition
- applyApply Phase 1 CJC-1295 + Ipamorelin reconstitution, dosing, and injection timing to reawaken the GH pulse across Weeks 1-4
- applyApply Phase 2 layering of IGF-1 LR3 bilateral site injection and MK-677 onto restored GH baseline across Weeks 5-10
- evaluateEvaluate how testosterone, free T3, and cortisol status gate the responsiveness of any GH/IGF-1 protocol
- analyzeInterpret IGF-1, fasting glucose, body composition, and metabolic markers as leading vs lagging indicators of protocol response
- applyManage MK-677-driven glucose elevation and insulin sensitivity drift during the Phase 2 recomp window
- applyExecute injection site rotation, training split alignment, and weekly rhythm that match the Phase 1 GH-pulse restoration window
- evaluateDiagnose clear, partial, and non-responder lab patterns and select the corresponding next-cycle protocol adjustment
- createCreate a low-dose pulse and cycling maintenance protocol that preserves recomp gains without HPA or insulin desensitization
- understandExplain the mechanistic distinction between systemic GH-driven IGF-1 elevation and local IGF-1 LR3 hyperplasia signaling
Chapters · 10
- 01What's actually happening in adult muscle growth
- 02The upstream lever — restoring pulsatile GH
- 03Phase 1 reset — CJC-1295 + Ipamorelin foundation (Week 1-4)
- 04Phase 2 rebuild — IGF-1 LR3 + MK-677 (Week 5–10)
- 05The supporting axis androgens thyroid and recovery hormones
- 06The labs that matter IGF 1 body comp and metabolic markers
- 07Chapter 7 — Weeks 1-4 execution: the daily and weekly rhythm
- 08Weeks 5-10 execution — layering IGF-1 LR3 and MK-677
- 09Chapter 9 — Adjusting based on labs: three response scenarios
- 10Maintenance — the sustained recomp protocol
Research use only · Not medical advice