Half-Life Decay
Every compound decays. See it before you pin.
Plot multi-dose pharmacokinetic decay across any half-life. Steady-state Cmax and Cmin rendered in real-time. This is the engine inside DoseCraft Pro, publicly demoed.
Time to steady state
~5 doses
≈ 4–5 half-lives to reach ~95% of Cmax,ss
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Track this in DoseCraftWhy half-life matters for peptide protocols▼
Half-life (t½) is the time it takes for serum concentration to drop by 50%. Every compound has one — BPC-157 is ~30 minutes, CJC-1295 with DAC is ~8 days. Two compounds at the same dose but different half-lives produce radically different exposure curves.
The math is first-order elimination: C(t) = C₀ · (0.5)t / t½. With regular dosing, each new dose lands on top of residual from prior doses — the curve accumulates until it hits steady state at ~4–5 half-lives.
Why this matters:
- Short-acting peptides (BPC-157, Ipamorelin) need multiple daily injections to maintain coverage.
- Long-acting ones (CJC-1295-DAC, Semaglutide, Tirzepatide) build up over weeks — Cmax keeps climbing on weekly dosing until SS.
- Stacking two long-acting compounds with overlapping mechanisms can silently push you way past the intended therapeutic window.
- Cmin (trough) at steady state tells you if you're getting continuous activity or pulsed peaks.
Note: this tool assumes volume of distribution = 1, so concentrations are shown in dose-relative units. The shape of the curve is accurate — absolute serum levels require Vd data per compound, which DoseCraft Pro carries for 90+ peptides.
For research use only. Not for human consumption. Not evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. DoseCraft is an informational tool — not medical advice.
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Track this calculator’s output on a real protocol. Pharmacokinetic math, 90+ compounds, vendor trust layer.