COA (Certificate of Analysis)
Also known as: certificate of analysis · lab report
A third-party laboratory report documenting the purity, identity, and mass of a peptide batch.
The COA is the single most important vendor trust signal in peptide sourcing. A legitimate COA is issued by an independent laboratory (not the vendor's internal lab), lists the specific batch number matching the vial, reports HPLC purity percentage, and includes a mass spectrometry identity confirmation. A 'COA' that lacks any of these elements is effectively worthless.
In practitioner audits we've reviewed, fraudulent COAs typically fail on batch mismatch — the same COA is reused across multiple batches with the date photoshopped. Verifying a COA by contacting the testing lab directly is the gold standard; DoseCraft's vendor trust scoring captures lab verification as a core input.
Related Terms
HPLC (High-Performance Liquid Chromatography)
An analytical technique that separates, identifies, and quantifies compounds in a sample based on differential affinity with a chromatographic column.
Mass Spectrometry
An analytical technique that ionizes a compound and measures the mass-to-charge ratio of its fragments to confirm molecular identity.
Vendor Trust Score
A composite metric evaluating peptide vendor reliability based on COA verification, batch consistency, shipping quality, and community feedback.
Batch Variance
The observed variability in purity, potency, or mass accuracy between different production lots of the same peptide from the same vendor.
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