Maintenance Dose
Also known as: maintenance · steady-state dose
The ongoing dose used to sustain target tissue exposure after any loading or titration phase is complete.
Maintenance dose is the dose at which the protocol settles for the bulk of its duration. For titrated compounds, maintenance is reached at the top of the titration schedule or earlier if side effects cap escalation. For non-titrated protocols, maintenance is the dose used from day one.
Maintenance is the dose that matters for long-term analysis. Early-cycle bloodwork reflects loading or titration conditions; maintenance-phase bloodwork reflects actual sustained protocol impact. Comparison across protocols should always be maintenance-to-maintenance, not start-dose-to-start-dose.
Related Terms
Loading Phase
The initial period of a protocol during which elevated or frequent dosing rapidly builds tissue exposure to a target level.
Titration
The gradual adjustment of a peptide dose — typically starting low and stepping up — to minimize side effects while establishing effective exposure.
Steady State
The point at which the rate of peptide administration equals the rate of elimination, producing a stable average plasma concentration.
On-Cycle
The active phase of a peptide cycle during which the compound is being administered.
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