On-Cycle
Also known as: during cycle · active cycle
The active phase of a peptide cycle during which the compound is being administered.
On-cycle is the measurement window: baseline bloodwork before start, subjective tracking throughout, and ideally mid-cycle bloodwork to catch drift before it becomes a problem. Most protocol errors are caught during on-cycle review rather than post-cycle — waiting until the end to discover a lipid or kidney marker moved the wrong direction is a recoverable but avoidable mistake.
On-cycle dose adjustments (titration up, de-escalation for side effects) are normal and expected. A cycle is not a commitment to rigid dosing; it's a commitment to systematic observation within a defined window.
Related Terms
Off-Cycle
The pause phase of a peptide cycle during which no compound is administered, allowing receptor recovery and isolated outcome measurement.
Cycle
A defined period of peptide administration followed by a planned pause, structured to manage receptor sensitivity and measure effects.
Titration
The gradual adjustment of a peptide dose — typically starting low and stepping up — to minimize side effects while establishing effective exposure.
Loading Phase
The initial period of a protocol during which elevated or frequent dosing rapidly builds tissue exposure to a target level.
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