CJC-1295 (no DAC) + GHRP-2
Mod GRF 1-29 + GHRP-2 / Modified GRF + GHRP-2 / CJC/GHRP-2 combo
A synergistic combination of a GHRH analog (CJC-1295 without DAC, aka Mod GRF 1-29) and a GH-releasing peptide (GHRP-2). CJC-1295 amplifies the GH pulse via GHRH receptor, while GHRP-2 initiates the pulse via ghrelin receptor. Together they produce a GH release 3–5x greater than either alone. The gold standard research peptide combination for GH optimization in the biohacking community.
Half-life
CJC-1295 no DAC: ~30 min; GHRP-2: ~15–25 min
Typical Dose
100 mcg CJC-1295 + 100–300 mcg GHRP-2 per injection
180/300Route
subcutaneous
Category
growth_hormone
Evidence Overview
Strength of evidence across clinical, expert, and experimental lanes.
How CJC-1295 (no DAC) + GHRP-2 is dosed in practice
Usually taken by subcutaneous (SubQ) injection. Typical range: 100 mcg CJC-1295 + 100–300 mcg GHRP-2 per injection. Half-life: CJC-1295 no DAC: ~30 min; GHRP-2: ~15–25 min. Each card gives the dose, frequency and duration from one evidence lane: Clinical (human trials), Expert (practitioner protocols) or Experimental (early or animal data). These ranges describe what has been studied or used; they are not a prescription.
Work out the units to draw with the reconstitution calculator, how long a vial lasts with the vial duration calculator, and how levels fall between doses with the half-life calculator.
The most popular GH optimization peptide combination in clinical practice. Practitioners dose before bed to augment the natural GH pulse during deep sleep. Fasting state recommended for injection (carbs blunt GH release). Some practitioners add ipamorelin as a third component.
- Anti-aging medicine practitioners — GH optimization protocols
- Sports medicine clinics — recovery and body composition protocols
- Clinical GH Peptide Protocols — Practitioner Consensus
Community gold standard for GH optimization. Users report improved sleep quality, faster recovery, fat loss, and skin improvements. GHRP-2 increases appetite more than ipamorelin, which some users consider a benefit for mass building and others a drawback.
- Reddit r/Peptides — CJC/GHRP-2 comprehensive guide
- MESO-Rx forums — GH peptide comparison threads
- Biohacking community body composition tracking data
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Upgrade to ProSafety & Contraindications
- Active cancer or history of cancer (GH promotes tumor growth)
- Uncontrolled diabetes (GH increases insulin resistance)
- Pregnancy or breastfeeding
CJC-1295 (no DAC) + GHRP-2: common questions
What is CJC-1295 (no DAC) + GHRP-2?
A synergistic combination of a GHRH analog (CJC-1295 without DAC, aka Mod GRF 1-29) and a GH-releasing peptide (GHRP-2). CJC-1295 amplifies the GH pulse via GHRH receptor, while GHRP-2 initiates the pulse via ghrelin receptor. Together they produce a GH release 3–5x greater than either alone. The gold standard research peptide combination for GH optimization in the biohacking community.
How is CJC-1295 (no DAC) + GHRP-2 dosed?
CJC-1295 (no DAC) + GHRP-2 is usually taken by subcutaneous (SubQ) injection. Typical range in DoseCraft's library: 100 mcg CJC-1295 + 100–300 mcg GHRP-2 per injection. Expert (practitioner protocols): 100 mcg CJC + 100–300 mcg GHRP-2, 2–3x/day; 2–3 times daily: AM fasted, post-workout, and pre-bed; 12–16 week cycles with 4-week breaks. Experimental (early or animal data): 100/100–200 mcg per injection; 2–3 times daily; 12–16 weeks, cycling recommended. These ranges describe what has been studied or used; they are not a prescription.
Is CJC-1295 (no DAC) + GHRP-2 FDA-approved?
No. CJC-1295 (no DAC) + GHRP-2 is not approved by the FDA for any use in people.
What is the half-life of CJC-1295 (no DAC) + GHRP-2?
DoseCraft's library lists a half-life of CJC-1295 no DAC: ~30 min; GHRP-2: ~15–25 min. Half-life sets how often a compound is dosed and how long it takes to clear: about five half-lives.
Who should not use CJC-1295 (no DAC) + GHRP-2?
Listed contraindications: Active cancer or history of cancer (GH promotes tumor growth); Uncontrolled diabetes (GH increases insulin resistance); Pregnancy or breastfeeding.
Free Guides for CJC-1295 (no DAC) + GHRP-2
Information is for educational purposes only. Always consult a licensed healthcare provider before starting any peptide regimen.
Page updated . How we grade evidence: methodology.