Testosterone Enanthate
Test E / Delatestryl
The most widely used testosterone ester globally for TRT and performance. Slightly shorter half-life than cypionate, making it popular in European and international protocols. Excellent clinical track record.
Half-life
5–8 days
Typical Dose
100–250 mg/week
150/250Route
intramuscular
Category
sexual_health
Evidence Overview
Strength of evidence across clinical, expert, and experimental lanes.
How Testosterone Enanthate is dosed in practice
Usually taken by intramuscular injection. Typical range: 100–250 mg/week. Half-life: 5–8 days. Each card gives the dose, frequency and duration from one evidence lane: Clinical (human trials), Expert (practitioner protocols) or Experimental (early or animal data). These ranges describe what has been studied or used; they are not a prescription.
Work out the units to draw with the reconstitution calculator, how long a vial lasts with the vial duration calculator, and how levels fall between doses with the half-life calculator.
Label dosing is 50–400 mg IM every 2–4 weeks. A SubQ autoinjector form is approved at 75 mg weekly, adjusted to trough levels.
- Drug label (testosterone enanthate injection)
- Drug label (Xyosted)
Interchangeable with cypionate in clinical practice. Some practitioners prefer enanthate for its slightly faster clearance allowing quicker dose adjustments. Split dosing protocol identical to cypionate.
- Testosterone replacement therapy practitioner consensus
- International Society for Sexual Medicine guidelines
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Upgrade to ProSafety & Contraindications
- Prostate or breast cancer
- Polycythemia (hematocrit > 54%)
- Severe untreated sleep apnea
- Pregnancy (Category X)
Testosterone Enanthate: common questions
What is Testosterone Enanthate?
The most widely used testosterone ester globally for TRT and performance. Slightly shorter half-life than cypionate, making it popular in European and international protocols. Excellent clinical track record.
How is Testosterone Enanthate dosed?
Testosterone Enanthate is usually taken by intramuscular injection. Typical range in DoseCraft's library: 100–250 mg/week. Clinical (human trials): 50–400 mg IM (label); 75 mg SubQ weekly by autoinjector, adjusted in 25 mg steps; Every 2–4 weeks (IM); once weekly (autoinjector); Ongoing replacement. Expert (practitioner protocols): 100–200 mg/week (split doses); 2x per week; Ongoing — lifetime protocol. These ranges describe what has been studied or used; they are not a prescription.
Is Testosterone Enanthate FDA-approved?
Yes. Testosterone Enanthate is an FDA-approved prescription medicine; uses outside its approved indication are off-label.
What is the half-life of Testosterone Enanthate?
DoseCraft's library lists a half-life of 5–8 days. Half-life sets how often a compound is dosed and how long it takes to clear: about five half-lives.
Who should not use Testosterone Enanthate?
Listed contraindications: Prostate or breast cancer; Polycythemia (hematocrit > 54%); Severe untreated sleep apnea; Pregnancy (Category X).
Free Guides for Testosterone Enanthate
Information is for educational purposes only. Always consult a licensed healthcare provider before starting any peptide regimen.
Page updated . How we grade evidence: methodology.